Affordable Access

deepdyve-link deepdyve-link
Publisher Website

Nanoroughened plasmonic films for enhanced biosensing detection.

Authors
  • Le Moal, Eric
  • Lévêque-Fort, Sandrine
  • Potier, Marie-Claude
  • Fort, Emmanuel
Type
Published Article
Journal
Nanotechnology
Publisher
IOP Publishing
Publication Date
Jun 03, 2009
Volume
20
Issue
22
Pages
225502–225502
Identifiers
DOI: 10.1088/0957-4484/20/22/225502
PMID: 19436093
Source
Medline
License
Unknown

Abstract

Although fluorescence is the prevailing labeling technique in biosensing applications, sensitivity improvement is still a striving challenge. We show that coating standard microscope slides with nanoroughened silver films provides a high fluorescence signal enhancement due to plasmonic interactions. As a proof of concept, we applied these films with tailored plasmonic properties to DNA microarrays. Using common optical scanning devices, we achieved signal amplifications of more than 40-fold.

Report this publication

Statistics

Seen <100 times