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Nanomaterial-based multiplex optical sensors.

Authors
  • Pei, Xiaojing1
  • Tao, Guangyu
  • Wu, Xi
  • Ma, Yurou
  • Li, Rongsheng
  • Li, Na
  • 1 College of Chemistry and Materials Engineering, Beijing Technology and Business University, Beijing 100048, P. R. China. , (China)
Type
Published Article
Journal
The Analyst
Publisher
The Royal Society of Chemistry
Publication Date
Jun 21, 2020
Volume
145
Issue
12
Pages
4111–4123
Identifiers
DOI: 10.1039/d0an00392a
PMID: 32490466
Source
Medline
Language
English
License
Unknown

Abstract

The drive for a simultaneous analysis of multiple targets with excellent accuracy and efficiency, which is often required in both basic biomedical research and clinical applications, demands the development of multiplexed bioassays with desired throughput. With the development of nanotechnologies, innovative multiplex optical bioassays have been achieved. Nanomaterials exhibit unique physical and chemical properties such as easily tunable size, large surface-to-volume ratio, excellent catalysis and the desired signal transduction mechanism, which makes them excellent candidates for the fabrication of novel optical nanoprobes. This mini review summarizes nanomaterial-based optical multiplex sensors from the last 5 years. Specific optical techniques covered in this review are fluorescence, surface-enhanced Raman scattering (SERS), localized surface plasmon resonance (LSPR), chemiluminescence (CL), and the multimodality with fundamentals and examples.

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