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NaCl-preferring NZB/B1NJ mice and NaCl-avoiding CBA/J mice have similar amiloride inhibition of chorda tympani responses to NaCl.

Authors
  • Ninomiya, Y
  • Bachmanov, A A
  • Yatabe, A
  • Beauchamp, G K
Type
Published Article
Journal
Chemical senses
Publication Date
Aug 01, 1998
Volume
23
Issue
4
Pages
411–415
Identifiers
PMID: 9759527
Source
Medline
License
Unknown

Abstract

Integrated chorda tympani nerve responses to NaCl were studied in two mouse strains, an NaCl-preferring NZB/B1NJ and an NaCl-avoiding CBA/J. The NaCl responses of both strains had similar magnitude and were suppressed by amiloride to a similar extent. This suggests that peripheral gustatory responsiveness to NaCl is not the only mechanism underlying mouse strain variation in NaCl acceptance.

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