Myocarditis related to Campylobacter jejuni infection: A case report

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Myocarditis related to Campylobacter jejuni infection: A case report

Publisher
BioMed Central
Publication Date
Jul 17, 2003
Source
PMC
Keywords
Disciplines
  • Biology
  • Medicine
License
Unknown

Abstract

1471-2334-3-16.fm ral ss BioMed CentBMC Infectious Diseases Open AcceCase report Myocarditis related to Campylobacter jejuni infection: A case report Christy Cunningham and Christine H Lee* Address: Department of Pathology and Molecular Medicine, McMaster University, St. Joseph's Healthcare, 50 Charlton Avenue East, Hamilton, Ontario, L8N 4A6, Canada Email: Christy Cunningham - [email protected]; Christine H Lee* - [email protected] * Corresponding author Abstract Background: Myocarditis can develop as a complication of various infections and is most commonly linked to enterovirus infections. Myocarditis is rarely associated with bacterial infections; salmonellosis and shigellosis have been the most frequently reported bacterial cause. We report a case of myocarditis related to Campylobacter jejuni enteritis. Case Presentation: A 30-year-old previously healthy man presented with a history of prolonged chest pain radiating to the jaw and the left arm. Five days prior to the onset of chest pain, he developed bloody diarrhea, fever and chills. Creatine kinase (CK) and CK-MB were elevated to 289 U/L and 28.7 µg/L. Troponin I was 30.2 µg/L. The electrocardiogram (ECG) showed T wave inversion in the lateral and inferior leads. The chest pain resolved within 24 hours of admission. The patient had a completely normal ECG stress test. The patient was initiated on ciprofloxacin 500 mg po bid when Campylobacter jejuni was isolated from the stool. Diarrhea resolved within 48 hours of initiation of ciprofloxacin. The diagnosis of Campylobacter enteritis and related myocarditis was made based on the clinical and laboratory results and the patient was discharged from the hospital in stable condition. Conclusion: Myocarditis can be a rare but severe complication of infectious disease and should be considered as a diagnosis in patients presenting with chest pain and elevated cardiac enzymes in the absence of underlying coronary disease. It can lead to cardiomyopat

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