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Myocardial dysfunction in hypothyroid children.

Authors
  • Farooki, Z Q
  • Hoffman, W H
  • Perry, B L
  • Green, E W
Type
Published Article
Journal
American journal of diseases of children (1960)
Publication Date
Jan 01, 1983
Volume
137
Issue
1
Pages
65–68
Identifiers
PMID: 6681526
Source
Medline
License
Unknown

Abstract

Eleven children with primary hypothyroidism were studied by echocardiography. Eight patients had pericardial effusion. Systolic time intervals (preejection period-ejection time ratio and left ventricular isovolumic contraction time) were suggestive of abnormal myocardial function. Asymmetric septal hypertrophy without left ventricular out-flow obstruction (ventricular septal-left ventricular posterior wall diastolic thickness ratio, greater than 1.3) was present in two hypothyroid children. After full replacement therapy, these cardiac abnormalities reversed to normal. Our data suggest that the myopericardial response to hypothyroidism in children is similar to that seen in adults.

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