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Mycotic aneurysm of the thoracic aorta due to Aspergillus terreus: case report and review.

Authors
Type
Published Article
Journal
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America
Publication Date
Volume
31
Issue
5
Pages
1144–1148
Identifiers
PMID: 11073743
Source
Medline

Abstract

Mycotic aneurysms of the aorta caused by fungi are uncommon. We describe an unusual case of aortic aneurysm infection caused by Aspergillus terreus, which most likely spread from an adjacent pulmonary focus. Successful treatment included partial pneumonectomy, resection of the aneurysm with graft repair, and prolonged sequential administration of amphotericin B and itraconazole. A review of the published experience with aortic aneurysms caused by Aspergillus species is also presented. When invasive aspergillosis is suspected in proximity to areas with major vascular structures in immunocompromised patients, further investigation to rule out vascular invasion may be warranted. If the diagnosis is confirmed, aggressive and prompt treatment with antifungal agents combined with surgical debridement is essential to improve outcome.

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