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Mycoses in northeastern Brazil: epidemiology and prevalence of fungal species in 8 years of retrospective analysis in Alagoas.

Authors
  • de Albuquerque Maranhão, Fernanda Cristi...1
  • Oliveira-Júnior, Jorge Belém2
  • Dos Santos Araújo, Maria Anilda3
  • Silva, Denise Maria Wanderlei4
  • 1 Universidade Federal de Alagoas, Instituto de Ciências Biológicas e da Saúde (ICBS), Departamento de Microbiologia, Laboratório de Microbiologia Clínica (LMC), Maceió, AL, 57022-222, Brazil. [email protected] , (Brazil)
  • 2 Fundação Oswaldo Cruz (Fiocruz), Centro de Pesquisas Aggeu Magalhães, Departamento de Parasitologia, Laboratório de Biologia Celular e Molecular, Recife, PE, Brazil. , (Brazil)
  • 3 Centro Universitário Tiradentes, Maceió, AL, Brazil. , (Brazil)
  • 4 Universidade Federal de Alagoas, Instituto de Ciências Biológicas e da Saúde (ICBS), Departamento de Microbiologia, Laboratório de Micologia (LabMicol), Maceió, AL, Brazil. , (Brazil)
Type
Published Article
Journal
Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology]
Publication Date
Oct 01, 2019
Volume
50
Issue
4
Pages
969–978
Identifiers
DOI: 10.1007/s42770-019-00096-0
PMID: 31140098
Source
Medline
Keywords
Language
English
License
Unknown

Abstract

Superficial and cutaneous mycoses are common in tropical countries, caused by dermatophytes, yeast, and non-dermatophyte molds in different clinical specimens. In order to define the epidemiology of mycoses and the profile of their etiological agents in Alagoas (northeastern Brazil) between 2009 and 2016, we obtained data of patients from the main laboratories of Alagoas, by examining clinical samples with direct microscopy and culture on Sabouraud dextrose agar and Chromagar®Candida. A total of 3316 patients were confirmed with mycoses (595 men/2716 women) and 40.25 of average age. Positive samples totaled 3776, mainly vaginal secretion (1593/42.2%), toenails (876/23.2%), and fingernails (589/15.6%). Yeasts were the most isolated (3129/82.9%), including 3012 Candida spp. (79.8%), 57 Malassezia spp. (1.5%), 42 Trichosporon sp. (1.1%), 10 Geotrichum spp. (0.3%), and 8 Rhodotorula spp. (0.2%). Candida albicans was the most frequent species (715/18.9%), followed by C. krusei (194/5.1%), C. tropicalis (24/0.6%), and 2079 unspecified species (55.1%). Among 17.1% filamentous fungi, 14.8% dermatophytes were distributed as 211 Trichophyton sp. (5.6%), 125 T. rubrum (3.3%), 106 T. tonsurans (2.8%), 72 T. mentagrophytes (1.9%), 2 Microsporum sp. (0.1%), 15 M. canis (0.4%), and 26 Epidermophyton sp. (0.7%). Other fungi represented the minority: Fusarium sp. and Aspergillus sp. These are the first clinical data on the Alagoas population affected by fungi pathogens, confirming a higher incidence of candidiasis (mainly vulvovaginal and onychomycosis) and dermatophytes, providing a better understanding of different mycoses in northeastern Brazil.

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