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The mutagenic effect of caprolactam in the spot test with (T x HT) F1 mouse embryos.

Authors
Type
Published Article
Journal
Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis
0027-5107
Publisher
Elsevier
Publication Date
Volume
224
Issue
3
Pages
369–371
Identifiers
PMID: 2811928
Source
Medline

Abstract

The mouse spot test was used to investigate the in vivo mutagenicity of caprolactam. Among offspring treated with 500 mg/kg, the frequency of spots was increased over controls in 4 separate experiments, leading to the conclusion that caprolactam is mutagenic in the spot test.

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