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Mussel-inspired nanozyme catalyzed conductive and self-setting hydrogel for adhesive and antibacterial bioelectronics

Authors
  • Jia, Zhanrong1
  • Lv, Xuanhan1
  • Hou, Yue1
  • Wang, Kefeng2
  • Ren, Fuzeng3
  • Xu, Dingguo2
  • Wang, Qun4
  • Fan, Kelong5, 6
  • Xie, Chaoming1
  • Lu, Xiong1
  • 1 Key Lab of Advanced Technologies of Materials, Ministry of Education, School of Materials Science and Engineering, Southwest Jiaotong University, Chengdu, 610031, Sichuan, China
  • 2 National Engineering Research Center for Biomaterials, Sichuan University, Chengdu, 610064, China
  • 3 Department of Materials Science and Engineering, Southern University of Science and Technology, Shenzhen, Guangdong, 518055, China
  • 4 College of Life Science and Biotechnology, Mianyang Teachers' College, Mianyang, 621006, China
  • 5 CAS Engineering Laboratory for Nanozyme, Key Laboratory of Protein and Peptide Pharmaceuticals, Institute of Biophysics, Chinese Academy of Sciences, Beijing, 100101, China
  • 6 Nanozyme Medical Center, School of Basic Medical Sciences, Zhengzhou University, Zhengzhou, 450001, China
Type
Published Article
Journal
Bioactive Materials
Publisher
KeAi Publishing
Publication Date
Feb 13, 2021
Volume
6
Issue
9
Pages
2676–2687
Identifiers
DOI: 10.1016/j.bioactmat.2021.01.033
PMID: 33665500
PMCID: PMC7895678
Source
PubMed Central
Keywords
License
Unknown

Abstract

• The mussel-inspired nanozyme with ultrasmall size was developed by the in-situ reduction of Ag NP with TA. • The mussel-inspired nanozyme exhibited catalytic dynamic antibacterial activity. • The mussel-inspired nanozyme triggered self-gelation of hydrogel without external stimuli. • The mussel-inspired nanozyme endowed the hydrogel with adhesiveness. • The nanozyme enabled the hydrogel to be used as a multifunctional adhesive bioelectronic.

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