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Multivalent glycocyclopeptides: toward nano-sized glycostructures.

Authors
  • Daskhan, Gour Chand1
  • Berthet, Nathalie1
  • Thomas, Baptiste1
  • Fiore, Michele1
  • Renaudet, Olivier2
  • 1 Univ. Grenoble Alpes, DCM, 38000 Grenoble, France; CNRS, DCM, 38000 Grenoble, France. , (France)
  • 2 Univ. Grenoble Alpes, DCM, 38000 Grenoble, France; CNRS, DCM, 38000 Grenoble, France; Institut Universitaire de France, 103 Boulevard Saint-Michel, 75005 Paris, France. Electronic address: [email protected] , (France)
Type
Published Article
Journal
Carbohydrate research
Publication Date
Mar 20, 2015
Volume
405
Pages
13–22
Identifiers
DOI: 10.1016/j.carres.2014.07.017
PMID: 25498201
Source
Medline
Keywords
Language
English
License
Unknown

Abstract

Cyclopeptides have recently emerged as attractive molecular scaffolds for the multivalent presentation of carbohydrates in a well-defined constrained spatial orientation. This mini-review describes the last advances on the synthesis and the biological applications of these particular structures, going from low molecular weight glycoclusters to fully synthetic nano-sized glycodendrimers. Copyright © 2014 Elsevier Ltd. All rights reserved.

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