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Multi-site benchmarking of clinical 13C RF coils at 3T

  • Sánchez-Heredia, Juan Diego1
  • Olin, Rie B.1
  • McLean, Mary A.2
  • Laustsen, Christoffer3
  • Hansen, Adam E.4
  • Hanson, Lars G.1, 5
  • Ardenkjær-Larsen, Jan Henrik1, 6
  • 1 Department of Health Technology, Technical University of Denmark, Kgs. Lyngby, Denmark
  • 2 Cancer Research UK Cambridge Institute, University of Cambridge, Cambridge, UK
  • 3 MR Research Centre, Department of Clinical Medicine, Aarhus University, Aarhus, Denmark
  • 4 Department of Clinical Physiology, Nuclear Medicine and PET, Rigshospitalet, University of Copenhagen, Copenhagen, Denmark
  • 5 Danish Research Centre for Magnetic Resonance, Centre for Functional and Diagnostic Imaging and Research, Copenhagen University Hospital Hvidovre, Denmark
  • 6 GE Healthcare, Brøndby, Denmark
Published Article
Journal of Magnetic Resonance
Publication Date
Sep 01, 2020
DOI: 10.1016/j.jmr.2020.106798
PMID: 32755748
PMCID: PMC7501735
PubMed Central


A quality assurance protocol for RF coils is proposed, which can be used for volume (Tx/Rx) and surface (Rx) coils. Following this protocol, a benchmarking of seven coils (from three different MR sites) dedicated to 13C MRI at 3T is reported. Coil performance is particularly important for 3T MRI at the 13C frequency, since the coil-to-sample noise ratio is typically high. The coils are evaluated experimentally using the proposed protocol based on MR spectroscopic imaging performed with two different phantoms: one head-shaped, and one with cylindrical shape and nearly twice the volume of the first one. To achieve an unbiased SNR comparison of volume and array coils, coil combination was done using sensitivity profiles extracted from the data. SNR, noise correlation matrices and example g-factor maps are reported. For globally calibrated, equal excitation angles, the measured SNR shows large differences for the volume coils of up to 115% at the phantom center for a head phantom. The arrays show lower differences in superficial SNR. The sample surface depth at which the volume coils outperform the arrays is estimated to 7 cm, and SNR furthest away from the coil surface is 28% lower for the best array compared to the best volume coil. A broad set of coils for 13C at 3T have been benchmarked. The results reported, and the method used to benchmark them, should guide the 13C community to choose the most suitable coil for a given experiment.

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