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Multiple skull metastases from hepatocellular carcinoma successfully treated with radiotherapy.

Authors
  • Nozaki, Ichiro1
  • Tsukada, Toshiyuki
  • Nakamura, Yuichi
  • Takanaka, Tsuyoshi
  • Yamada, Masahito
Type
Published Article
Journal
Internal medicine (Tokyo, Japan)
Publication Date
Jan 01, 2010
Volume
49
Issue
23
Pages
2631–2634
Identifiers
PMID: 21139306
Source
Medline
License
Unknown

Abstract

We report a Japanese man who presented with multiple cranial nerve palsies with hepatitis B virus-related multiple hepatocellular carcinoma (HCC). He presented with right III, IV, VI, IX, X, and XII cranial nerve palsies. Metastases involving the clivus and the right occipital bone from HCC were diagnosed by the findings of magnetic resonance imaging of the head, cerebral angiography, and 2-deoxy-2-[(18)F]fluoro-D-glucose positron emission tomography/computed tomography. In this case, over one-year survival and improvement of neurological signs were achieved by radiotherapy in spite of multiple skull metastases, which are extremely rare.

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