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Multicentre evaluation of magnetic resonance imaging supported transperineal prostate biopsy in biopsy-naïve men with suspicion of prostate cancer.

Authors
  • Hansen, Nienke L1
  • Barrett, Tristan1, 2
  • Kesch, Claudia3
  • Pepdjonovic, Lana4
  • Bonekamp, David5
  • O'Sullivan, Richard6
  • Distler, Florian3
  • Warren, Anne1, 7
  • Samel, Christina8
  • Hadaschik, Boris3
  • Grummet, Jeremy4
  • Kastner, Christof1, 9
  • 1 CamPARI Clinic, Addenbrooke's Hospital and University of Cambridge, Cambridge, UK.
  • 2 Department of Radiology, Addenbrooke's Hospital and University of Cambridge, Cambridge, UK.
  • 3 Department of Urology, University Hospital Heidelberg, Heidelberg, Germany. , (Germany)
  • 4 Australian Urology Associates and Department of Surgery, Central Clinical School, Monash University, Melbourne, Vic., Australia. , (Australia)
  • 5 Department of Radiology, German Cancer Research Center (DKFZ), Heidelberg, Germany. , (Germany)
  • 6 Healthcare Imaging and Monash University, Melbourne, Vic., Australia. , (Australia)
  • 7 Department of Pathology, Addenbrooke's Hospital and University of Cambridge, Cambridge, UK.
  • 8 Institute of Medical Statistics, Informatics and Epidemiology, University Hospital Cologne, Cologne, Germany. , (Germany)
  • 9 Department of Urology, Addenbrooke's Hospital and University of Cambridge, Cambridge, UK.
Type
Published Article
Journal
British Journal of Urology
Publisher
Wiley (Blackwell Publishing)
Publication Date
Oct 11, 2017
Identifiers
DOI: 10.1111/bju.14049
PMID: 29024425
Source
Medline
Keywords
License
Unknown

Abstract

MRI-based transperineal biopsy performed at high-volume tertiary care centres with a significant experience of prostate mpMRI and image-guided targeted biopsies yielded high detection rates of Gleason score 7-10 cancer. Prostate biopsies may not be needed for men with low PSAD and an unsuspicious MRI. In patients with high probability lesions, combined targeted and systematic biopsies are recommended.

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