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[Multicenter study of the in vitro antibacterial activity of ceftazidime on gram-negative bacilli].

Authors
  • Deforges, L
  • Le Van Thoi, J
  • Soussy, C J
  • Duval, J
  • Thabaut, A
  • Meyran, M
  • Acar, J F
  • Kitzis, M D
  • Fleurette, J
  • Coulet, M
Type
Published Article
Journal
Pathologie Biologie
Publisher
Elsevier
Publication Date
May 01, 1983
Volume
31
Issue
5
Pages
375–378
Identifiers
PMID: 6353327
Source
Medline
License
Unknown

Abstract

This work reports a multicenter study of antibacterial activity of ceftazidime, a new third generation cephalosporin, on hospital Gram negative rods. Enterobacteriaceae are very sensitive to ceftazidime with a maximum number of strains inhibited by 1 microgram/ml or less (modal MIC 0, 125 microgram/ml); some resistant strains are observed, particularly among Enterobacter and Citrobacter. Activity of ceftazidime on Pseudomonas aeruginosa is superior to other third generation cephalosporins; modal MIC is 1 microgram/ml and 88% of the strains are inhibited by 4 microgram/ml or less. Acinetobacter are less sensitive to ceftazidime, with a modal MIC of 8 microgram/ml.

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