Multicenter evaluation of a semiautomated, standardized assay for detection of hepatitis B virus DNA in blood donations.
- Published Article
Journal of clinical microbiology
- Publication Date
Jun 01, 2005
We evaluated the COBAS Ampliscreen hepatitis B virus (HBV) test using standards, seroconversion panels, consecutive donations, and samples from patients with abnormal alanine aminotransferase and chronic hepatitis C. Specificity was 100% and sensitivity was 20 IU/ml. In seroconversion panels, HBV DNA was detected up to 4 to 18 days before HBsAg, suggesting that this assay is useful in shortening the infectious window phase.
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The corresponding record at NLM can be accessed at https://www.ncbi.nlm.nih.gov/pubmed/15956441