Mucosal Immune System of Cattle: All Immune Responses Begin Here.
Department of Veterinary and Biomedical Sciences, South Dakota State University, PO Box 2175, SAR Room 125, North Campus Drive, Brookings, SD 57007, USA. Electronic address: [email protected]
Department of Biology and Microbiology, South Dakota State University, Brookings, SD 57007, USA.
- Published Article
The Veterinary clinics of North America. Food animal practice
- Publication Date
Nov 01, 2019
This article discusses key concepts important for mucosal immunity. The mucosa is the largest immune organ of the body. The mucosal barrier (the tight junctions and the "kill zone") along with the mucosa epithelial cells maintaining an anti-inflammatory state are essential for the mucosal firewall. The microbiome (the microorganisms that are in the gastrointestinal, respiratory, and reproductive tract) is essential for immune development, homeostasis, immune response, and maximizing animal productivity. Mucosal vaccination provides an opportunity to protect animals from most infectious diseases because oral, gastrointestinal, respiratory, and reproductive mucosa are the main portals of entry for infectious disease. Copyright © 2019 Elsevier Inc. All rights reserved.
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This record was last updated on 11/11/2019 and may not reflect the most current and accurate biomedical/scientific data available from NLM.
The corresponding record at NLM can be accessed at https://www.ncbi.nlm.nih.gov/pubmed/31590896