mRNA polyadenylation and its coupling to other RNA processing reactions and to transcription.
- Authors
- Type
- Published Article
- Journal
- Current Opinion in Cell Biology
- Publisher
- Elsevier
- Publication Date
- Jun 01, 1999
- Volume
- 11
- Issue
- 3
- Pages
- 352–357
- Identifiers
- PMID: 10395555
- Source
- Medline
- License
- Unknown
Abstract
Eukaryotic mRNA precursors are processed at their 3' ends by a coupled cleavage/polyadenylation reaction. In recent years, most of the factors involved in 3'-end processing have been identified and evidence has been presented for the coupling of mRNA 3'-end formation to capping, splicing and transcription. These links are important for the quality control of the mRNA during synthesis.
