Affordable Access

Publisher Website

The mRNA decay pathway regulates the expression of the Flo11 adhesin and biofilm formation in Saccharomyces cerevisiae.

Authors
Type
Published Article
Journal
Genetics
1943-2631
Publisher
The Genetics Society of America
Publication Date
Volume
191
Issue
4
Pages
1387–1391
Identifiers
DOI: 10.1534/genetics.112.141432
PMID: 22595243
Source
Medline

Abstract

Regulation of the FLO11 adhesin is a model for gene expression control by extracellular signals and developmental switches. We establish that the major mRNA decay pathway regulates FLO11 expression. mRNA deadenylation of transcriptional repressors of FLO11 by the exonuclease Ccr4 keeps their levels low, thereby allowing FLO11 transcription.

There are no comments yet on this publication. Be the first to share your thoughts.

Statistics

Seen <100 times
0 Comments