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MR in vivo imaging of oxygen suppression effect of soft contact lens on the human cornea.

Authors
Type
Published Article
Journal
Magnetic Resonance Imaging
0730-725X
Publisher
Elsevier
Publication Date
Volume
18
Issue
3
Pages
357–360
Identifiers
PMID: 10745146
Source
Medline
License
Unknown

Abstract

The O(2) suppression effect of a soft contact lens on the human cornea was measured using dynamic magnetic resonance imaging (MRI) of the anterior chamber transcorneally exposed to O(2). Dynamic T(1)-weighted fast spin echo imaging of anterior chambers (TR = 2 s, TE = 15 ms, 5-mm slice) was performed both before and during oxygen supply to a full goggle placed on the face of volunteers wearing a soft contact lens on one eye and nothing on the other eye as a control. Within 15 min after O(2) administration, significantly lower intensity changes were obtained in the anterior chambers of the eyes with the contact lens than in those of the eyes without one, suggesting that dynamic MRI of the anterior chamber transcorneally exposed to O(2) can be used to evaluate the O(2) suppression effect of a soft contact lens on the cornea.

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