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Mortality and morbidity in treated hypertensive type 2 diabetic patients with micro- or macroproteinuria.

Authors
  • Sawicki, P T
  • Mühlhauser, I
  • Didjurgeit, U
  • Reimann, M
  • Bender, R
  • Berger, M
Type
Published Article
Journal
Diabetic medicine : a journal of the British Diabetic Association
Publication Date
Oct 01, 1995
Volume
12
Issue
10
Pages
893–898
Identifiers
PMID: 8846680
Source
Medline
License
Unknown

Abstract

In order to describe the natural history of high risk diabetic patients treated for hypertension we have followed a sequential sample of 100 hypertensive Type 2 diabetic patients with elevated urinary protein excretion ( > or = 60 mg 24 h-1) for a period of 1-7 years. Antihypertensive treatment was instituted in all patients and, in addition, the patients were offered the possibility of participation in an intensified antihypertensive therapy programme. After a mean follow-up of 4 years overall mortality was 13%. Nineteen percent of all patients experienced a cardiovascular event and 7% a cerebrovascular event. In conclusion, in this study the overall mortality was lower that previously reported in proteinuric Type 2 diabetic patients. Antihypertensive treatment may account for this outcome.

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