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Mortality and incidence of cancer during 10-year follow-up of the Scandinavian Simvastatin Survival Study (4S).

Authors
  • Strandberg, Timo E
  • Pyörälä, Kalevi
  • Cook, Thomas J
  • Wilhelmsen, Lars
  • Faergeman, Ole
  • Thorgeirsson, Gudmundur
  • Pedersen, Terje R
  • Kjekshus, John
Type
Published Article
Journal
The Lancet
Publisher
Elsevier
Publication Date
Jan 01, 2004
Volume
364
Issue
9436
Pages
771–777
Identifiers
PMID: 15337403
Source
Medline
License
Unknown

Abstract

Simvastatin treatment for 5 years in a placebo-controlled trial, followed by open-label statin therapy, was associated with survival benefit over 10 years of follow-up compared with open-label statin therapy for the past 5 years only. No difference was noted in mortality from and incidence of cancer between the original simvastatin group and placebo group.

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