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Morphologic and cytochemical study of L929 cell variants with different metastasizing ability in C3HA/Hab mice.

Authors
  • Rodríguez, T
  • Rengifo, E
  • Gavilondo, J
  • Tormo, B
  • Fernández, A
Type
Published Article
Journal
Neoplasma
Publication Date
Jan 01, 1984
Volume
31
Issue
3
Pages
271–279
Identifiers
PMID: 6377099
Source
Medline
License
Unknown

Abstract

A morphologic (phase-contrast, TEM and SEM) and cytochemical study was performed on L929 cell variants that show different malignant behavior and lung colonization ability in C3HA/Hab mice. The paper presents and discusses the correlation between enhanced lung colonization ability and the expression in culture of rounded, risen, less attached morphologies. Also, a diminution in the activity of mitochondrial enzymes and number of these cell organelles was found for the cell variant selected for enhanced lung colonization ability.

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