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Morphine, morphine-6-glucuronide, and morphine-3-glucuronide in cerebrospinal fluid and plasma after epidural administration of morphine.

Authors
  • Kalman, S
  • Metcalf, K
  • Eintrei, C
Type
Published Article
Journal
Regional anesthesia
Publication Date
Jan 01, 1997
Volume
22
Issue
2
Pages
131–136
Identifiers
PMID: 9089854
Source
Medline
License
Unknown

Abstract

No evidence of spinal metabolism of morphine could be found. Rapid distribution of morphine to CSF and plasma occurred after epidural administration. No value of initial CSF morphine concentrations for prediction of analgesic requirements could be demonstrated.

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