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Morphine infusion after pediatric cardiac surgery.

Authors
  • Lynn, A M
  • Opheim, K E
  • Tyler, D C
Type
Published Article
Journal
Critical Care Medicine
Publisher
Ovid Technologies (Wolters Kluwer) - Lippincott Williams & Wilkins
Publication Date
Oct 01, 1984
Volume
12
Issue
10
Pages
863–866
Identifiers
PMID: 6435955
Source
Medline
License
Unknown

Abstract

After cardiac surgery, 44 children received a continuous iv infusion of morphine sulfate at 10 to 30 micrograms/kg X h. During weaning from assisted ventilation and during spontaneous ventilation serum morphine levels less than 30 ng/ml were not associated with elevated PaCO2. Five extubated patients breathed spontaneously, and 35 patients were weaned from assisted to spontaneous ventilation with normal PaCO2 while receiving morphine by infusion, indicating that morphine did not interfere with spontaneous ventilation. In 12 older children who gave verbal pain scores, pain was relieved at serum morphine levels above 12 ng/ml.

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