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[Monoclonal antibodies which recognize herpes simplex virus and their possible diagnostic application].

Authors
  • Pupo Antúnez, M
  • Hermida Díaz, C
  • Morier Díaz, L
  • García Infante, S
  • Resik Aguirre, S
Type
Published Article
Journal
Revista cubana de medicina tropical
Publication Date
Jan 01, 1997
Volume
49
Issue
3
Pages
181–185
Identifiers
PMID: 9685985
Source
Medline
License
Unknown

Abstract

It is reported the obtention of monoclonal antibodies, which are capable of recognizing HSV-1 and HSV-2 viruses, by the conventional technology of cellular fusion. The monoclonal antibodies of highest positivity according to the indirect immunofluorescence technique were partially characterized. It was determined the neutralizing capacity of 2 of them (278-F7 and 70-G10), which were used to identify isolations of clinical specimens by indirect immunofluorescence. These monoclonal antibodies recognized HSV-1 up to a dilution of 1:2 560.

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