Affordable Access

Monoclonal antibodies against RNA-dependent DNA polymerase from myeloblastosis-associated viruses.

Authors
Type
Published Article
Journal
Folia biologica
Publication Date
Volume
33
Issue
2
Pages
87–92
Identifiers
PMID: 2439388
Source
Medline

Abstract

Two lines of hybridomas, RT-12 and RT-14, secreting monoclonal antibodies against the reverse transcriptase from myeloblastosis-associated viruses have been prepared. The monoclonal antibodies RT-12 and RT-14 specifically react with reverse transcriptase, as has been shown by radioimmunoassay and enzyme-linked immunoassay techniques after SDS-PAGE and blotting to nitrocellulose membranes. It has been shown that antigenic determinants for RT-12 and RT-14 are stable to SDS denaturation, hence they belong to a linear type; they are located on the alpha subunit of the enzyme.

There are no comments yet on this publication. Be the first to share your thoughts.

Statistics

Seen <100 times
0 Comments