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Are the monamine oxidase inhibitors facing extinction?

Authors
  • O'Reilly, R L
Type
Published Article
Journal
Canadian journal of psychiatry. Revue canadienne de psychiatrie
Publication Date
Apr 01, 1991
Volume
36
Issue
3
Pages
186–189
Identifiers
PMID: 2059937
Source
Medline
License
Unknown

Abstract

The use of monoamine oxidase inhibitors (MAOIs) in the province of Saskatchewan was compared for two years, 1978 and 1986, using the Saskatchewan Prescription Drug Plan data base. The percentage of the adult population receiving an MAOI decreased from 0.17% in 1978 to 0.07% in 1986. The use of both tricyclic antidepressants and the new generation antidepressants increased during the same period. Physicians appear to have selectively avoided using MAOIs for the elderly. Physicians who are not psychiatrists showed the greatest reduction in their use of the MAOIs. The data indicate an increasing reluctance to prescribe the MAOIs despite the recent resurgence of interest in these agents and the positive literature concerning their safety and efficacy.

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