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Molecular variability of group 1 and 5 grass pollen allergens between Pooideae species: implications for immunotherapy.

Authors
Type
Published Article
Journal
Clinical & Experimental Allergy
1365-2222
Publisher
Wiley Blackwell (Blackwell Publishing)
Publication Date
Volume
40
Issue
3
Pages
505–519
Identifiers
DOI: 10.1111/j.1365-2222.2009.03380.x
PMID: 19895591
Source
Medline
License
Unknown

Abstract

Major pollen allergens from distinct grass species bear both shared and species-restricted T and B cell immune epitopes. When compared with single extracts, a five grass pollen extract is thus more suitable for specific immunotherapy, as it contains a broader repertoire of the IgE epitopes to which patients are sensitized.

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