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Molecular regulation of mast cell development and maturation.

Authors
  • Liu, Chenxiong1
  • Liu, Zhigang
  • Li, Zhilong
  • Wu, Yaojiong
  • 1 Allergy and Immunology Institute, School of Medicine, Shenzhen University, Shenzhen, China. , (China)
Type
Published Article
Journal
Molecular Biology Reports
Publisher
Springer-Verlag
Publication Date
Apr 01, 2010
Volume
37
Issue
4
Pages
1993–2001
Identifiers
DOI: 10.1007/s11033-009-9650-z
PMID: 19644767
Source
Medline
License
Unknown

Abstract

Mast cells play a crucial role in the pathogenesis of allergic diseases. In recent years, tremendous progresses have been made in studies of mast cell origination, migration, proliferation, maturation and survival, and the cytokines regulating these activities. These advances have significantly improved our understandings to mast cell biology and to the molecular mechanisms of mast cells in the pathogenesis of allergic diseases.

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