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Molecular pathogenesis and therapy of polycythemia induced in mice by JAK2 V617F.

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eScholarship - University of California
Keywords
  • Medicine And Health Sciences
  • Amino Acid Substitution
  • Animals
  • Bone Marrow Transplantation
  • Disease Models, Animal
  • Enzyme Activation
  • Erythropoiesis
  • Humans
  • Janus Kinase 2: Antagonists & Inhibitors; Genetics; Metabolism
  • Leukocytosis: Blood; Etiology
  • Mice
  • Mice, Inbred Balb C
  • Mice, Inbred C57Bl
  • Mice, Knockout
  • Platelet Count
  • Point Mutation
  • Polycythemia Vera: Blood; Drug Therapy; Enzymology; Genetics
  • Primary Myelofibrosis: Etiology; Pathology
  • Protein Kinase Inhibitors: Therapeutic Use
  • Recombinant Proteins: Genetics; Metabolism
  • Transduction, Genetic
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Abstract

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