Affordable Access

deepdyve-link
Publisher Website

Molecular organization, regulation and function of tricellular junctions.

Authors
  • Higashi, Tomohito1
  • Chiba, Hideki2
  • 1 Department of Basic Pathology, Fukushima Medical University, Fukushima 960-1295, Japan. Electronic address: [email protected] , (Japan)
  • 2 Department of Basic Pathology, Fukushima Medical University, Fukushima 960-1295, Japan. , (Japan)
Type
Published Article
Journal
Biochimica et biophysica acta. Biomembranes
Publication Date
Dec 05, 2019
Pages
183143–183143
Identifiers
DOI: 10.1016/j.bbamem.2019.183143
PMID: 31812626
Source
Medline
Language
English
License
Unknown

Abstract

Tricellular junctions are specialized cell-cell junctions formed at sites where three epithelial or endothelial cells make contact at their apical side. By holding three cells together, tricellular junctions contribute to the maintenance of epithelial barrier function and mechanical integrity. In addition, recent studies have uncovered new functions of tricellular junctions at both cellular and physiological levels. In this review, we describe the architecture and molecular components of tricellular junctions and discuss how tricellular junctions participate in various biological processes. Copyright © 2019. Published by Elsevier B.V.

Report this publication

Statistics

Seen <100 times