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Molecular evolution of kobuviruses in cats

Authors
  • Cho, Yoon-Young1, 2
  • Lim, Seong-In1
  • Kim, Yong Kwan1
  • Song, Jae-Young1
  • Lee, Joong-Bok2
  • An, Dong-Jun1
  • 1 Animal and Plant Quarantine Agency, Anyang, Gyeonggi, 430-824, Republic of Korea , Anyang (South Korea)
  • 2 Konkuk University, Department of Infectious Diseases, College of Veterinary Medicine, Seoul, 143-701, Republic of Korea , Seoul (South Korea)
Type
Published Article
Journal
Archives of Virology
Publisher
Springer-Verlag
Publication Date
Nov 15, 2014
Volume
160
Issue
2
Pages
537–541
Identifiers
DOI: 10.1007/s00705-014-2259-0
Source
Springer Nature
Keywords
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Abstract

Aichi virus, a causative agent of human gastroenteritis, is one of a number of animal viruses belonging to the genus Kobuvirus within the family Picornaviridae. The kobuvirus genome encodes several structural and nonstructural proteins; the capsid proteins encoded by the VP1 gene are key immunogenic factors. Here, we used the VP1 region to determine substitution rates and the time to the most recent common ancestor (TMRCA) by comparing feline kobuvirus (FKoVs) sequences with kobuvirus sequences isolated from members of other species. The substitution rate for FKoVs was 1.29 × 10−2 substitutions/site/year (s/s/y) and the TMRCA was 5.3 years.

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