Affordable Access

Molecular determinants of Listeria monocytogenes virulence.

Authors
  • Dussurget, Olivier
  • Pizarro-Cerda, Javier
  • Cossart, Pascale
Type
Published Article
Journal
Annual review of microbiology
Publication Date
Jan 01, 2004
Volume
58
Pages
587–610
Identifiers
PMID: 15487949
Source
Medline
License
Unknown

Abstract

Listeria monocytogenes is the etiological agent of listeriosis, a severe human foodborne infection characterized by gastroenteritis, meningitis, encephalitis, abortions, and perinatal infections. This gram-positive bacterium is a facultative intracellular pathogen that induces its own uptake into nonphagocytic cells and spreads from cell to cell using an actin-based motility process. This review covers both well-established and recent advances in the characterization of L. monocytogenes virulence determinants and their role in the pathophysiology of listeriosis.

Report this publication

Statistics

Seen <100 times