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Molecular cloning of two novel protein kinase genes from Arabidopsis thaliana.

Authors
Type
Published Article
Journal
Biochimica et Biophysica Acta
0006-3002
Publisher
Elsevier
Publication Date
Volume
1216
Issue
1
Pages
9–14
Identifiers
PMID: 8218420
Source
Medline

Abstract

We have isolated two novel protein kinase genes, MHK and NAK, from the plant Arabidopsis thaliana by using low stringency hybridization with the catalytic domain of a putative plant receptor protein kinase. Sequence analysis of the cDNAs reveals that MHK is a member of the cdc2+ family of protein kinases and is particularly similar to the mak gene of rats; mak encodes a protein kinase that may play a role in spermatogenesis. NAK encodes a candidate protein kinase that is similar to the oncogenes met and abl. The homology that these two Arabidopsis genes share with other protein kinases suggests that they may play a role in the regulation of plant growth and development.

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