A general method has been developed which, in theory, will make it possible to follow the inheritance of virtually all genes in human families. This method, based on genetic linkage, envisions the use of cloned single copy human deoxyribonucleic acid probes to reveal restriction fragment length polymorphisms as genetic markers. Such markers can be assembled into a linkage map which can be applied to analysis of inherited diseases. It is speculated that such a map might help to clarify the role that heredity plays in the etiology of epilepsy.
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This record was last updated on 07/01/2016 and may not reflect the most current and accurate biomedical/scientific data available from NLM.
The corresponding record at NLM can be accessed at https://www.ncbi.nlm.nih.gov/pubmed/6378616