Modulation of peripheral-type benzodiazepine receptor levels in a reperfusion injury pig kidney-graft model.
- Authors
- Type
- Published Article
- Journal
- Transplantation Journal
- Publisher
- Ovid Technologies (Wolters Kluwer) - Lippincott Williams & Wilkins
- Publication Date
- Dec 15, 2002
- Volume
- 74
- Issue
- 11
- Pages
- 1507–1515
- Identifiers
- PMID: 12490782
- Source
- Medline
- License
- Unknown
Abstract
This study indicates that PBR expression correlates with the quality of kidney preservation and might serve as an index of kidney and mitochondria viability. Moreover, these data suggest that PBR might be involved in membrane biogenesis during reperfusion. In addition, considering the identical localization of PBR in human and pig kidneys, these findings could have a direct application in human clinical settings of kidney pathology.
