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Modifying an immunogenic epitope on a therapeutic protein: a step towards an improved system for antibody-directed enzyme prodrug therapy (ADEPT)

Authors
  • Mayer, A1
  • Sharma, S K1
  • Tolner, B1
  • Minton, N P2
  • Purdy, D3
  • Amlot, P1, 4
  • Tharakan, G1
  • Begent, R H J1
  • Chester, K A1
  • 1 Cancer Research UK Targeting and Imaging Group, Department of Oncology, Royal Free and University College Medical School, University College London, Rowland Hill Street, London NW3 2PF, UK
  • 2 Institute of Infections, Immunity and Inflammation, University of Nottingham, Floor C, West Block, Queens Medical Centre, Nottingham NG7 2UH, UK
  • 3 Health Protection Agency, Porton Down, Salisbury, Wiltshire SP4 0JG, UK
  • 4 Department of Immunology, Royal Free and University College Medical School, University College London, Rowland Hill Street, London NW3 2PF, UK
Type
Published Article
Journal
British Journal of Cancer
Publisher
Springer Nature
Publication Date
May 25, 2004
Volume
90
Issue
12
Pages
2402–2410
Identifiers
DOI: 10.1038/sj.bjc.6601888
PMID: 15162148
PMCID: PMC2409521
Source
PubMed Central
Keywords
License
Unknown
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