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Modification of the swern oxidation: use of a recyclable, polystyrene bound sulfoxide.

Authors
  • Cole, Derek C
  • Stock, Joseph R
  • Kappel, Jo Anne
Type
Published Article
Journal
Bioorganic & Medicinal Chemistry Letters
Publisher
Elsevier
Publication Date
Jul 22, 2002
Volume
12
Issue
14
Pages
1791–1793
Identifiers
PMID: 12086818
Source
Medline
License
Unknown

Abstract

A method has been developed for the oxidation of sulfides to sulfoxides on polystyrene resin. The polystyrene bound sulfoxide may be used in Swern oxidation reactions, and the used reagent may be regenerated by oxidation with tert-butylhydrogen peroxide.

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