Modeling transcriptome dynamics in a complex world.
- Authors
- Type
- Published Article
- Journal
- Cell
- Publisher
- Elsevier
- Volume
- 151
- Issue
- 6
- Pages
- 1161–1162
- Identifiers
- DOI: 10.1016/j.cell.2012.11.031
- Source
- Ideker Lab
- License
- Unknown
Abstract
An accurate prediction of how extrinsic stimuli influence changes in gene expression has been challenging. In this issue, Nagano and colleagues successfully model genome-wide mRNA expression changes under variable environmental conditions in rice, raising hopes that scientists will soon be able to predict genome-wide transcriptional responses in a variety of organisms in uncontrolled real-world settings.