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Model identification of a template-directed peptide network for optimization in a continuous reactor.

Authors
  • Hernandez, Andres F1
  • Wagner, Michael J
  • Grover, Martha A
  • 1 School of Chemical & Biomolecular Engineering, Georgia Institute of Technology, 311 Ferst Dr. NW, Atlanta, GA 30332, USA. [email protected] , (Georgia)
Type
Published Article
Journal
Chemical Communications
Publisher
The Royal Society of Chemistry
Publication Date
Apr 14, 2014
Volume
50
Issue
29
Pages
3849–3851
Identifiers
DOI: 10.1039/c4cc00501e
PMID: 24590303
Source
Medline
License
Unknown

Abstract

The production rate and selectivity of a cross-catalytic peptide network are optimized in a simulated continuous reaction process, under a peptide solubility constraint. The steady state of this open process is not the equilibrium state, and the optimal solution employs diverse cooperative components.

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