MitoProt, a Macintosh application for studying mitochondrial proteins.
Ecole Normale Supérieure, Laboratoire de Génétique Moléculaire, CNRS URA 1302, Paris, France.
- Published Article
Computer applications in the biosciences : CABIOS
- Publication Date
The paper describes the Macintosh program MitoProt, which is suitable for studying mitochondrion-related proteins. MitoProt supplies a series of parameters that permit theoretical evaluation of mitochondrial targeting sequences, as well as calculation of the most hydrophobic fragment of 17 residues in the sequence, and a new parameter called mesohydrophobicity. The last two calculations are important for predicting the putative importability of a protein into mitochondria. Taken together, targeting sequence and hydrophobicity characteristics enable one to predict whether a given protein could be mitochondrial when no previous information on the nature of the sequence is available.
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This record was last updated on 07/07/2017 and may not reflect the most current and accurate biomedical/scientific data available from NLM.
The corresponding record at NLM can be accessed at https://www.ncbi.nlm.nih.gov/pubmed/8521054