Affordable Access

MitoProt, a Macintosh application for studying mitochondrial proteins.

Authors
  • 1
Type
Published Article
Journal
Computer applications in the biosciences : CABIOS
0266-7061
Publication Date
Volume
11
Issue
4
Pages
441–447
Identifiers
PMID: 8521054
Source
Medline

Abstract

The paper describes the Macintosh program MitoProt, which is suitable for studying mitochondrion-related proteins. MitoProt supplies a series of parameters that permit theoretical evaluation of mitochondrial targeting sequences, as well as calculation of the most hydrophobic fragment of 17 residues in the sequence, and a new parameter called mesohydrophobicity. The last two calculations are important for predicting the putative importability of a protein into mitochondria. Taken together, targeting sequence and hydrophobicity characteristics enable one to predict whether a given protein could be mitochondrial when no previous information on the nature of the sequence is available.

There are no comments yet on this publication. Be the first to share your thoughts.

Statistics

Seen <100 times
0 Comments