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Mitochondrial respiratory chain hepatopathies: role of liver transplantation. A case series of five patients.

Authors
  • De Greef, Elisabeth
  • Christodoulou, John
  • Alexander, Ian E
  • Shun, Albert
  • O'Loughlin, Edward V
  • Thorburn, David R
  • Jermyn, Vicki
  • Stormon, Michael O
Type
Published Article
Journal
JIMD reports
Publication Date
Jan 01, 2012
Volume
4
Pages
5–11
Identifiers
DOI: 10.1007/8904_2011_29
PMID: 23430890
Source
Medline
License
Unknown

Abstract

Hepatic MRCD has a variable presentation. Diagnosis requires the measurement of respiratory chain enzymes on tissue from liver biopsy. Whether to proceed to OLT is a difficult decision given a good outcome in a minority of cases, suggesting that MRCD should not be an absolute contraindication to liver transplantation.

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