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The mitochondrial DNA control region sequences from the Chinese sui population of southwestern China.

Authors
  • Yuhang Feng1
  • Zhang, Hongling1
  • Wang, Qiyan1
  • Yang, Meiqing1
  • Liu, Yubo1
  • Wang, Jie1
  • Huang, Jiang1
  • Ren, Zheng1
Type
Published Article
Journal
Annals of Human Biology
Publisher
Informa UK (Taylor & Francis)
Publication Date
Dec 21, 2021
Volume
48
Issue
7-8
Pages
635–640
Identifiers
DOI: 10.1080/03014460.2021.1994649
PMID: 34663140
Source
Medline
Keywords
Language
English
License
White

Abstract

Sui people are officially recognised people living in southwest China, but there has been a lack of genetic research, especially based on mitochondrial DNA data. To study the sequences and haplogroups of the mitochondrial DNA control region in a typical Sui population, with the aim of helping to promote the establishment of a forensic DNA analysis reference database in East Asia. We analysed 201 Sui individuals and observed the sequences of the mitochondrial DNA control region. We calculated and explained the haplotype frequencies, haplogroup distribution and pairwise Fst values between the Sui and 47 other populations in the world, in order to explore genetic polymorphisms and population relationships. 161 haplotypes were found in the Sui population, with frequencies of 0.0049-0.0199. All samples were assigned to 80 different haplogroups. The haplotype diversity and random matching probability were 0.999938 and 0.024729, respectively. The pairwise Fst values and correlation p-values of 48 populations showed that the Sui population was most closely related to the Miao population in Guizhou and the Han population in Henan, and closer to the Punjab population and Pukhtunkhwa population in Pakistan, and was significantly different from the other 43 groups. Compared with the other 43 groups, it is relatively isolated. Our results show that the study of mitochondrial DNA based on the analysis of matrilineal genetic structure of the Sui population can help to promote the establishment of a forensic DNA reference database in East Asia and provide reference for future anthropological research.

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