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miR-182 and miR-135b Mediate the Tumorigenesis and Invasiveness of Colorectal Cancer Cells via Targeting ST6GALNAC2 and PI3K/AKT Pathway.

Authors
  • Jia, Li1
  • Luo, Shihua2, 3
  • Ren, Xiang4
  • Li, Yang2
  • Hu, Jialei2
  • Liu, Bing2
  • Zhao, Lifen2
  • Shan, Yujia2
  • Zhou, Huimin2
  • 1 College of Laboratory Medicine, Dalian Medical University, Dalian, 116044, Liaoning Province, China. [email protected] , (China)
  • 2 College of Laboratory Medicine, Dalian Medical University, Dalian, 116044, Liaoning Province, China. , (China)
  • 3 Department of Traumatology, Shanghai Ruijin Hospital, Jiaotong University, Shanghai, 200025, China. , (China)
  • 4 College of Stomatology, Dalian Medical University, Dalian, 116044, Liaoning Province, China. , (China)
Type
Published Article
Journal
Digestive Diseases and Sciences
Publisher
Springer-Verlag
Publication Date
Dec 01, 2017
Volume
62
Issue
12
Pages
3447–3459
Identifiers
DOI: 10.1007/s10620-017-4755-z
PMID: 29030743
Source
Medline
Keywords
License
Unknown

Abstract

The miR-182/-135b/ST6GALNAC2/PI3K/AKT axis may serve as a predictive biomarker and a potential therapeutic target in CRC treatment.

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