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MiR-421, miR-155 and miR-650: emerging trends of regulation of cancer and apoptosis.

Authors
  • Farooqi, Ammad Ahmad
  • Qureshi, Muhammad Zahid
  • Coskunpinar, Ender
  • Naqvi, Syed Kamran-Ul-Hassan
  • Yaylim, Ilhan
  • Ismail, Muhammad
Type
Published Article
Journal
Asian Pacific journal of cancer prevention : APJCP
Publication Date
Jan 01, 2014
Volume
15
Issue
5
Pages
1909–1912
Identifiers
PMID: 24716910
Source
Medline
License
Unknown

Abstract

It is becoming progressively more understandable that between transcription and translation there lies another versatile regulator that quantitatively controls the expression of mRNAs. Identification of miRNAs as key regulators of wide ranging signaling cascades and modulators of different cell-type and context dependent activities attracted basic and clinical scientists to study modes and mechanisms in details. In line with this approach overwhelmingly increasing in vivo and in vitro studies are deepening our understanding regarding miR-421, mir-155 and miR-650 mediated regulation of cellular activities. We also attempt to provide an overview of long non coding RNAs.

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