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Microwave-assisted one-pot multi-component reaction: synthesis of novel and highly functionalized 3-(pyranyl)- and 3-(dihydropyridinyl)indole derivatives.

Authors
  • Borah, Pallabi1
  • Naidu, P Seetham
  • Majumder, Swarup
  • Bhuyan, Pulak J
  • 1 Medicinal Chemistry Division, CSIR-North East Institute of Science & Technology, Jorhat, 785006, Assam, India. , (India)
Type
Published Article
Journal
Molecular Diversity
Publisher
Springer-Verlag
Publication Date
Nov 01, 2014
Volume
18
Issue
4
Pages
759–767
Identifiers
DOI: 10.1007/s11030-014-9533-7
PMID: 25012814
Source
Medline
License
Unknown

Abstract

One-pot multi-component reaction of 3-cyanoacetyl indole, aromatic aldehydes and ethyl acetoacetate in the presence of InCl(3)/NH(4)OAc under microwave irradiation for 2-7 min afforded novel and highly functionalized 3-(pyranyl)- and 3-(dihydropyridinyl)indole derivatives, respectively, in good yield.

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