Microwave-assisted one-pot multi-component reaction: synthesis of novel and highly functionalized 3-(pyranyl)- and 3-(dihydropyridinyl)indole derivatives.
Medicinal Chemistry Division, CSIR-North East Institute of Science & Technology, Jorhat, 785006, Assam, India.
- Published Article
- Publication Date
Nov 01, 2014
One-pot multi-component reaction of 3-cyanoacetyl indole, aromatic aldehydes and ethyl acetoacetate in the presence of InCl(3)/NH(4)OAc under microwave irradiation for 2-7 min afforded novel and highly functionalized 3-(pyranyl)- and 3-(dihydropyridinyl)indole derivatives, respectively, in good yield.
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The corresponding record at NLM can be accessed at https://www.ncbi.nlm.nih.gov/pubmed/25012814