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Microtiter solid-phase radioimmunoassay for detection of Escherichia coli heat-labile enterotoxin.

Authors
  • Greenberg, H B
  • Sack, D A
  • Rodriguez, W
  • Sack, R B
  • Wyatt, R G
  • Kalica, A R
  • Horswood, R L
  • Chanock, R M
  • Kapikian, A Z
Type
Published Article
Journal
Infection and immunity
Publication Date
Sep 01, 1977
Volume
17
Issue
3
Pages
541–545
Identifiers
PMID: 332626
Source
Medline
License
Unknown

Abstract

The development of a microtiter solid-phase radioimmunoassay for the detection of Vibrio cholerae enterotoxin and heat-labile Escherichia coli enterotoxin is described. The test is based on the immunological similarity between V. cholerae toxin and E. coli heat-labile toxin. The assay is easy to perform, quantitative, and at least as sensitive and specific as the Y-1 adrenal cell system.

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