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Microstructural integrity of early- versus late-myelinating white matter tracts in medial temporal lobe epilepsy.

Authors
  • Lee, Chu-Yu
  • Tabesh, Ali
  • Benitez, Andreana
  • Helpern, Joseph A
  • Jensen, Jens H
  • Bonilha, Leonardo
Type
Published Article
Journal
Epilepsia
Publication Date
Oct 01, 2013
Volume
54
Issue
10
Pages
1801–1809
Identifiers
DOI: 10.1111/epi.12353
PMID: 24032670
Source
Medline
Keywords
License
Unknown

Abstract

These results suggest a developmentally based preferential susceptibility of late-myelinating WM tracts to damage in MTLE. Brain injury in epilepsy may be due to the pathologic effects of seizures in combination with regional WM vulnerability.

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