Affordable Access

deepdyve-link deepdyve-link
Publisher Website

Microjaponin, a new dihydroagarofuranoid sesquiterpene from the stem of Microtropis japonica with antituberculosis activity.

Authors
Type
Published Article
Journal
Chemistry & Biodiversity
1612-1880
Publisher
Wiley Blackwell (John Wiley & Sons)
Publication Date
Volume
11
Issue
8
Pages
1241–1246
Identifiers
DOI: 10.1002/cbdv.201400066
PMID: 25146767
Source
Medline
Keywords
License
Unknown

Abstract

A new dihydroagarofuran-based sesquiterpene, microjaponin (1), was isolated from the stem of Microtropis japonica. Its structure was determined by in-depth spectroscopic and mass-spectrometric analyses. Microjaponin (1) exhibited potent in vitro antituberculosis activity, with an MIC value of 12.5 μg/ml against Mycobacterium tuberculosis H37 Rv.

Statistics

Seen <100 times