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Microfluidic opportunities in printed electrolyte-gated transistor biosensors

Authors
  • Dorfman, Kevin D.
  • Adrahtas, Demetra Z.
  • Thomas, Mathew S.
  • Frisbie, C. Daniel
Type
Published Article
Journal
Biomicrofluidics
Publisher
American Institute of Physics
Publication Date
Jan 27, 2020
Volume
14
Issue
1
Identifiers
DOI: 10.1063/1.5131365
PMID: 32002104
PMCID: PMC6984978
Source
PubMed Central
License
Unknown

Abstract

Printed electrolyte-gated transistors (EGTs) are an emerging biosensor platform that leverage the facile fabrication engendered by printed electronics with the low voltage operation enabled by ion gel dielectrics. The resulting label-free, nonoptical sensors have high gain and provide sensing operations that can be challenging for conventional chemical field effect transistor architectures. After providing an overview of EGT device fabrication and operation, we highlight opportunities for microfluidic enhancement of EGT sensor performance via multiplexing, sample preconcentration, and improved transport to the sensor surface.

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